This is fatty acid amide, that occurs naturally in human body, animals and plants.
It is thought to be produced as a protective response to cellular injury and is usually up-regulated in disease states.
PEA produced internally is generally insufficient for treating chronic inflammatory diseases, so supplying this substance externally is an excellent therapeutic strategy to restore balance in the body.
PEA has widely documented effects:
The use of PEA is safe!
Multi-faceted effects
PEA has special mechanism of action that affects several pathways at different sites. It acts on the PPAR-α receptor, G protein-coupled receptor 55 (GPR55) and G protein 119 (GPR119). It also activates cannabinoid receptors 1 and 2 (CB1 and CB2) and vanilloid receptor channels 1. In addition, it inhibits mast cell activation.1
1(Clayton P, Hill M, Bogoda N, Subah S, Venkatesh R. Palmitoylethanolamide: A Natural Compound for Health Management. Int J Mol Sci. 2021 May 18;22(10):5305. doi: 10.3390/ijms22105305. PMID: 34069940; PMCID: PMC8157570.)
Due to synergistic interactions between several mechanisms, PEA exerts important therapeutic effects in both the central and peripheral nervous systems
More about PEA available from IMPAG
More efficient absorption thanks to special particle size - the powder is ultra-micronized, which means a particle size of less than 10 μm.
Applications
Dietary supplements for humans and dogs and cats, for example:
Forms
The product is packaged in 25 kg drums.
Applications